Correction to: Nature Biotechnology https://doi.org/10.1038/s41587-022-01254-w, published online 24 March 2022.

In the version of this article initially published, there was an error in the name of a mutation: “His840Arg” should have read “His840Ala.” The error has been corrected in the first paragraph of the Introduction and twice in the “Expanding the scope of ePPE using SpG Cas9” subsection of Results. The changes have been made in the HTML and PDF versions of the article.