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LIQUID BIOPSIES

Enhanced cancer detection from cell-free DNA

A new assay for cell-free DNA fragmentation improves prediction of gene expression in liquid biopsies.

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Fig. 1: Analysis of the diversity of fragment sizes.

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Correspondence to Y. M. Dennis Lo.

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Competing interests

Y.M.D.L. holds equity in DRA, Take2 and Grail/Illumina. Y.M.D.L. is a scientific cofounder of Grail. P.J. holds equity in DRA and Grail/Illumina. P.J. is a consultant to Take2. P.J. is a Director of KingMed Future. Patent royalties are received from Grail, Illumina, Sequenom, DRA, Take2 Health and Xcelom.

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Jiang, P., Lo, Y.M.D. Enhanced cancer detection from cell-free DNA. Nat Biotechnol 40, 473–474 (2022). https://doi.org/10.1038/s41587-021-01207-9

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