Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Patient preferences in the treatment of genitourinary cancers

Several newly approved therapies have substantially altered the treatment paradigm for multiple genitourinary cancers. Considering the existence of numerous possible treatment approaches, understanding which treatment attributes are most valued by each patient is crucial to physicians to recommend a cancer-directed treatment.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type



Prices may be subject to local taxes which are calculated during checkout


  1. Benjamin, D. J., Xu, A., Lythgoe, M. P. & Prasad, V. Cancer drug approvals that displaced existing standard-of-care therapies, 2016-2021. JAMA Netw. Open 5, e222265 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

  2. Ver Hoeve, E. S., Ali-Akbarian, L., Price, S. N., Lothfi, N. M. & Hamann, H. A. Patient-reported financial toxicity, quality of life, and health behaviors in insured US cancer survivors. Support. Care Cancer 29, 349–358 (2021).

    Article  PubMed  Google Scholar 

  3. George, D. J. et al. Patient preferences for treatment and outcomes in hormone-sensitive prostate cancer (HSPC) [abstract]. J. Clin. Oncol. 40 (Suppl. 16), e18757 (2022).

    Article  Google Scholar 

  4. Collins, S. P. et al. Identifying prostate cancer patient subgroups based on their preferences for key attributes of androgen deprivation therapies [abstract]. J. Clin. Oncol. 41 (Suppl. 6), 94 (2023).

    Article  Google Scholar 

  5. Grivas, P. et al. Preferences for first-line treatment of advanced urothelial carcinoma among US practicing oncologists and patients. Future Oncol. (2023).

    Article  PubMed  Google Scholar 

  6. Apolo, A. B. et al. Understanding drivers of treatment preferences in locally advanced or metastatic urothelial carcinoma: a qualitative interview study with patients, caregivers, and physicians [abstract]. J. Clin. Oncol. 41 (Suppl. 6), 492 (2023).

    Article  Google Scholar 

  7. Battle, D. et al. Patient preferences and expectations of systemic therapy in renal cell carcinoma [abstract]. J. Clin. Oncol. 38 (Suppl. 15), 5083 (2020).

    Article  Google Scholar 

  8. Vass, C. et al. Heterogeneity in physician and patient preferences for the treatment of renal cell carcinoma: evidence from latent class analysis [abstract]. J. Clin. Oncol. 41 (Suppl. 6), 661 (2023).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to David J. Benjamin.

Ethics declarations

Competing interests

A.R.K. declares stock and other ownership interests: ECOM Medical; consulting or advisory role: Exelixis, AstraZeneca, Bayer, Pfizer, Novartis, Genentech, Bristol Myers Squibb, EMD Serono, Immunomedics and Gilead Sciences; speakers’ bureau: Janssen, Astellas Medivation, Pfizer, Novartis, Sanofi, Genentech/Roche, Eisai, AstraZeneca, Bristol Myers Squibb, Amgen, Exelixis, EMD Serono, Merck, Seattle Genetics/Astellas, Myovant Sciences, Gilead Sciences and AVEO; research funding: Genentech, Exelixis, Janssen, AstraZeneca, Bayer, Bristol Myers Squibb, Eisai, Macrogenics, Astellas Pharma, BeyondSpring Pharmaceuticals, BioClin Therapeutics, Clovis Oncology, Bavarian Nordic, Seattle Genetics, Immunomedics and Epizyme; and travel, accommodations and/or expenses: Genentech, Prometheus, Astellas Medivation, Janssen, Eisai, Bayer, Pfizer, Novartis, Exelixis and AstraZeneca. D.J.B. declares no competing interests.

Rights and permissions

Reprints and Permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Benjamin, D.J., Rezazadeh Kalebasty, A. Patient preferences in the treatment of genitourinary cancers. Nat Rev Urol 20, 513–514 (2023).

Download citation

  • Published:

  • Issue Date:

  • DOI:


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing