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The unclear role of PET–CT in localized radiorecurrent prostate cancer

Prostate cancer recurrence is common after radical radiotherapy and the increasing use of novel, minimally invasive salvage treatments means that accurate detection and localization of radiorecurrent disease is vital in treatment planning and delivery. PET–CT is increasingly used to detect metastatic disease; however, data regarding its value for identifying and accurately characterizing intraprostatic recurrence need improvement.

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Correspondence to Taimur T. Shah.

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H.U.A. receives core funding from the UK National Institute of Health Research (NIHR) Imperial Biomedical Research Centre, the Wellcome Trust, the UK NIHR, the UK Medical Research Council, Cancer Research UK, Prostate Cancer UK, The Urology Foundation, the BMA Foundation, Imperial Healthcare Charity, Sonacare, Trod Medical and Sophiris Biocorp; has received a travel allowance from Sonacare; was a paid consultant for Sophiris Biocorp and Sonacare; and is a proctor for Rezūm treatment and cryotherapy for Boston Scientific. The other authors declare no competing interests.

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Light, A., Ahmed, H.U. & Shah, T.T. The unclear role of PET–CT in localized radiorecurrent prostate cancer. Nat Rev Urol 19, 573–574 (2022). https://doi.org/10.1038/s41585-022-00635-9

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