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INFECTION

PrEP for HIV: grade A for evidence but pending for impact

The US Preventive Services Task Force has issued a grade A recommendation that clinicians offer pre-exposure prophylaxis (PrEP) to people at high risk of acquiring HIV. Currently, many fewer individuals receive PrEP than those who would benefit from it; whether PrEP can have a real impact on reducing the global burden of HIV is yet to be determined.

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Correspondence to Jared M. Baeten.

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Competing interests

J.M.B. has led studies of pre-exposure prophylaxis with funding from the US National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), United States Agency for International Development (USAID) and the Bill & Melinda Gates Foundation and has served on advisory boards for Gilead Sciences and Merck. Funding to support the present work is from NIH grants R01 MH095587 and P30 AI027757.

Additional information

Related links

PrEPWatch: http://prepwatch.org

Prevention access campaign: https://www.preventionaccess.org/

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Baeten, J.M. PrEP for HIV: grade A for evidence but pending for impact. Nat Rev Urol 16, 570–571 (2019). https://doi.org/10.1038/s41585-019-0219-x

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