The US Preventive Services Task Force has issued a grade A recommendation that clinicians offer pre-exposure prophylaxis (PrEP) to people at high risk of acquiring HIV. Currently, many fewer individuals receive PrEP than those who would benefit from it; whether PrEP can have a real impact on reducing the global burden of HIV is yet to be determined.
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J.M.B. has led studies of pre-exposure prophylaxis with funding from the US National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), United States Agency for International Development (USAID) and the Bill & Melinda Gates Foundation and has served on advisory boards for Gilead Sciences and Merck. Funding to support the present work is from NIH grants R01 MH095587 and P30 AI027757.