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PARKINSON DISEASE

Changes in brain drainage systems are linked to Parkinson disease

Nature Reviews Neurology volume 17, page 131 (2021)Cite this article

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Two new studies, published in Nature Medicine and Movement Disorders, have shown that people with Parkinson disease (PD) exhibit alterations in brain lymphatic and glymphatic drainage systems. The findings suggest that dysfunction of brain drainage pathways represents both an early biomarker and a potential therapeutic target for PD.

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  • Louveau, A. et al. Structural and functional features of central nervous system lymphatic vessels. Nature 523, 337–341 (2015)

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  • Wardlaw, J. M. et al. Perivascular spaces in the brain: anatomy, physiology and pathology. Nat. Rev. Neurol. 16, 137–153 (2020)

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  1. Nature Reviews Neurology http://www.nature.com/nrneurol/

    Heather Wood

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  1. Heather Wood
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Correspondence to Heather Wood.

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Wood, H. Changes in brain drainage systems are linked to Parkinson disease. Nat Rev Neurol 17, 131 (2021). https://doi.org/10.1038/s41582-021-00466-z

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  • DOI: https://doi.org/10.1038/s41582-021-00466-z

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