Mutations cause phenotypic changes by perturbing the organization of molecular networks and the functions that emerge from these networks. A model of a cell based on molecular interactions will be required in order to understand the molecular mechanisms underlying complex traits.
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Diss, G. Towards attaining a quantitative and mechanistic model of a cell. Nat Rev Mol Cell Biol 21, 301–302 (2020). https://doi.org/10.1038/s41580-020-0229-9
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DOI: https://doi.org/10.1038/s41580-020-0229-9
