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150 years of Darwin’s theory of intercellular flow of hereditary information

Nature Reviews Molecular Cell Biologyvolume 19pages749750 (2018) | Download Citation

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In 1868, Charles Darwin published his Pangenesis theory, which proposed a mechanism for the flow of hereditary information between cells and generations. Pangenesis has since been disputed, but emerging evidence of cell-to-cell communication urges the reconsideration of this 150-year-old theory.

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Acknowledgements

The authors thank R. M. Roberts for constructive comments and members of the Chen laboratory for discussions. Research in the Chen laboratory is supported by the NIH (R01HD092431).

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Affiliations

  1. Henan Collaborative Innovation Center of Modern Biological Breeding, Henan Institute of Science and Technology, Xinxiang, China

    • Yongsheng Liu
  2. Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada

    • Yongsheng Liu
  3. Department of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA

    • Qi Chen

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Competing interests

The authors declare no competing interests.

Corresponding author

Correspondence to Qi Chen.

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DOI

https://doi.org/10.1038/s41580-018-0072-4

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