New filovirus disease classification and nomenclature

The recent large outbreak of Ebola virus disease (EVD) in Western Africa resulted in greatly increased accumulation of human genotypic, phenotypic and clinical data, and improved our understanding of the spectrum of clinical manifestations. As a result, the WHO disease classification of EVD underwent major revision.

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The authors thank Laura Bollinger (US National Institutes of Health (NIH)/US National Institute of Allergy and Infectious Diseases (NIAID) Integrated Research Facility at Fort Detrick, Frederick, MD, USA) for critically reviewing the manuscript. This work was supported in part through Battelle Memorial Institute’s prime contract with the NIAID under Contract No. HHSN272200700016I (J.H.K.). This project was funded in part with federal funds from the National Cancer Institute, NIH, under Contract No. HHSN261200800001E (I.C.). G.I. is grateful for support from the Italian Ministry of Health, grant Ricerca Corrente, Research Programme n.1. The UK Public Health Rapid Support Team (D.G.B.) is funded by the UK Department of Health and Social Care.

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Correspondence to Jens H. Kuhn.

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The views and conclusions contained in this document are those of the authors and should not be interpreted as necessarily representing the official views, assertions, opinions or policies, either expressed or implied, of the US Department of Defense, US Department of Health and Human Services (National Institutes of Health; Centers for Disease Control and Prevention), US Uniformed Services University, UK National Health System, the UK National Institute for Health Research, the UK Department of Health and Social Care or of the institutions and companies affiliated with the authors. In no event shall any of these entities have any responsibility or liability for any use, misuse, inability to use, or reliance upon the information contained herein. Some authors are employees of the U.S. Government and as such under the provisions of 17 U.S.C. 105, copyright protection is not available for this work. Mention of trade names, commercial products, or organizations does not imply endorsement by the US Government.

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Kuhn, J.H., Adachi, T., Adhikari, N.K.J. et al. New filovirus disease classification and nomenclature. Nat Rev Microbiol 17, 261–263 (2019).

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