Correction to: Nature Reviews Immunology https://doi.org/10.1038/s41577-021-00511-4, published online 04 February 2021.

The original version of this In Brief stated that patients with severe COVID-19 produced “virus-specific antibodies that appeared to functionally block the production of ISG-expressing cells…”. However, this is not correct; the original publication reported that these antibodies had a very broad pattern of self-reactivity. Therefore, the term “virus-specific” has been removed.