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LIVER PHYSIOLOGY

A relaxin-based nanotherapy for liver fibrosis

Nature Nanotechnology volume 16, pages 365–366 (2021)Cite this article

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Targeting of the peptide hormone relaxin to injured mouse liver, via a nanoparticle/gene therapy approach, switches pro-fibrotic hepatic macrophages to a restorative phenotype that orchestrates tissue repair.

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Fig. 1: Macrophages as a central hub in the regulation of liver fibrosis.

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Authors and Affiliations

  1. Centre for Inflammation Research, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK

    Jonathan A. Fallowfield & Prakash Ramachandran

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  1. Jonathan A. Fallowfield
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  2. Prakash Ramachandran
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Correspondence to Jonathan A. Fallowfield.

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Fallowfield, J.A., Ramachandran, P. A relaxin-based nanotherapy for liver fibrosis. Nat. Nanotechnol. 16, 365–366 (2021). https://doi.org/10.1038/s41565-020-00832-w

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