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On the issue of transparency and reproducibility in nanomedicine

Nature Nanotechnology volume 14, pages 629–635 (2019)Cite this article

A Publisher Correction to this article was published on 29 July 2019

A Publisher Correction to this article was published on 09 July 2019

This article has been updated

Following our call to join in the discussion over the suitability of implementing a reporting checklist for bio–nano papers, the community responds.

Below we report short extracts highlighting the main messages of the correspondences we received. The interested readers can find the complete pieces in the accompanying Supplementary Information.

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  • 29 July 2019

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

  • 09 July 2019

    An amendment to this paper has been published and can be accessed via a link at the top of the paper

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Acknowledgements

Kimberly S. Butler, Hon S. Leong and C. Jeffrey Brinker: Sandia National Laboratories is a multi-mission laboratory managed and operated by National Technology and Engineering Solutions of Sandia, LLC, a wholly owned subsidiary of Honeywell International, Inc., for the US Department of Energy’s National Nuclear Security Administration under contract DENA0003525. Any subjective views or opinions that might be expressed in the paper do not necessarily represent the views of the US Department of Energy or the US government.

Adriele Prina-Mello, Ruth Schmid, Peter Wick, Fanny Caputo, Patrick Boisseau, Rachael M. Crist and Scott E. McNeil: the view expressed in this Correspondence is reflective of the European Nanomedicine Characterisation Laboratory (EUNCL EC-H2020 ref. 654190) and the REFINE consortium (REFINE EC-H2020 ref. 761104). The work of authors Rachael M. Crist and Scott E. McNeil has been funded in whole or in part with Federal funds from the National Cancer Institute, National Institutes of Health, under contract no. HHSN261200800001E. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products or organizations imply endorsement by the US government.

Author information

Authors and Affiliations

  1. Department of Urology, Mayo Clinic, Rochester, MN, USA

    Hon S. Leong

  2. Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA

    Hon S. Leong

  3. Department of Nanobiology, Sandia National Laboratories, Albuquerque, NM, USA

    Kimberly S. Butler

  4. Center for Micro-Engineered Materials, University of New Mexico Albuquerque, Albuquerque, NM, USA

    C. Jeffrey Brinker

  5. Departments of Chemical and Biological Engineering, University of New Mexico, Albuquerque, NM, USA

    C. Jeffrey Brinker

  6. Department of Molecular Genetics and Microbiology, University of New Mexico, Albuquerque, NM, USA

    C. Jeffrey Brinker

  7. UNM Comprehensive Cancer Center, University of New Mexico, Albuquerque, NM, USA

    C. Jeffrey Brinker

  8. Cardiovascular Research Group, School of Healthcare Science, Manchester Metropolitan University, Manchester, UK

    May Azzawi

  9. British Society for Nanomedicine https://www.britishsocietynanomedicine.org

    May Azzawi, Steve Conlan, Christine Dufés, Andrew Owen, Steve Rannard & Chris Scott

  10. Institute of Life Science, Swansea University Medical School, Swansea University, Swansea, UK

    Steve Conlan

  11. Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK

    Christine Dufés

  12. Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK

    Andrew Owen

  13. Department of Chemistry, School of Physical Sciences, University of Liverpool, Liverpool, UK

    Steve Rannard

  14. Centre for Cancer Research and Cell Biology, Queen’s University of Belfast, Belfast, UK

    Chris Scott

  15. National Center for Nanoscience and Technology of China, Beijing, China

    Chunying Chen

  16. Cancer Research Technology Program, Nanotechnology Characterization Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA

    Marina A. Dobrovolskaia

  17. Laboratory of Animal Sciences Program, Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA

    Marina A. Dobrovolskaia & Serguei V. Kozlov

  18. Trinity Translational Medicine Institute, Department of Clinical Medicine, Trinity College Dublin, Dublin, Ireland

    Adriele Prina-Mello

  19. Laboratory for Biological Characterisation of Advanced Materials, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland

    Adriele Prina-Mello

  20. Nanomedicine Group, Advanced Materials and Bioengineering Research (AMBER) centre, Centre for Research on Adaptive Nanostructures and Nanodevices, Trinity College Dublin, Dublin, Ireland

    Adriele Prina-Mello

  21. SINTEF Industry, Trondheim, Norway

    Ruth Schmid

  22. Empa — Swiss Federal Laboratories for Materials Science and Technology, St Gallen, Switzerland

    Peter Wick

  23. University Grenoble Alpes, CEA, LETI, Grenoble, Switzerland

    Fanny Caputo & Patrick Boisseau

  24. Cancer Research Technology Program, Nanotechnology Characterization Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA

    Rachael M. Crist & Scott E. McNeil

  25. Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

    Bengt Fadeel

  26. Institute of Occupational Medicine, Edinburgh, UK

    Lang Tran

  27. Department of Environmental Engineering, Technical University of Denmark, Kongens Lyngby, Denmark

    Steffen Foss Hansen, Nanna B. Hartmann, Lauge P. W. Clausen, Lars M. Skjolding & Anders Baun

  28. Department of Environmental Science and Analytical Chemistry (ACES), Stockholm University, Stockholm, Sweden

    Marlene Ågerstrand

  29. Department of Bioengineering, California Nanosystems Institute, University of California, Los Angeles, Los Angeles, CA, USA

    Zhen Gu

  30. School of Pharmacy, Queen’s University Belfast, Belfast, UK

    Dimitrios A. Lamprou

  31. Institute of Science and Technology in Medicine, Keele University, Keele, UK

    Clare Hoskins

  32. Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA

    Leaf Huang

  33. Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China

    Wantong Song

  34. State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, China

    Huiliang Cao & Xuanyong Liu

  35. Otto Schott Institute of Materials Research, Friedrich Schiller University Jena, Jena, Germany

    Huiliang Cao & Klaus D. Jandt

  36. Department of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX, USA

    Wen Jiang

  37. Department of Neurosurgery, The University of Texas MD Anderson Cancer, Houston, TX, USA

    Betty Y. S. Kim

  38. Department of Chemistry and Biochemistry, Santa Clara University, Santa Clara, CA, USA

    Korin E. Wheeler

  39. School of Geography Earth and Environmental Sciences, University of Birmingham, Birmingham, UK

    Andrew J. Chetwynd & Iseult Lynch

  40. School of Pharmacy, Newcastle University, Newcastle upon Tyne, UK

    Seyed Moein Moghimi

  41. Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK

    Seyed Moein Moghimi

  42. Division of NanoMedicine, Department of Medicine, California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA, USA

    André Nel & Tian Xia

  43. Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, USA

    Paul S. Weiss

  44. Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA

    Paul S. Weiss

  45. Department of Materials Science and Engineering, California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA, USA

    Paul S. Weiss

  46. i3S — Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal

    Bruno Sarmento & José das Neves

  47. INEB – Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal

    Bruno Sarmento & José das Neves

  48. Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

    Hélder A. Santos

  49. Dosage Form Design and Development, MedImmune, LLC, Gaithersburg, MD, USA

    Luis Santos

  50. Wyss Institute of Biologically Inspired Engineering, Harvard University, Cambridge, MA, USA

    Samir Mitragotri

  51. Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA

    Steve Little

  52. George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel

    Dan Peer

  53. School of Pharmacy, Northeastern University, Boston, MA, USA

    Mansoor M. Amiji

  54. CIMUS Research Institute, Universidade de Santiago de Compostela, Santiago de Compostela, Spain

    Maria José Alonso

  55. Adolphe Merkle Institute, University of Fribourg, Fribourg, Switzerland

    Alke Petri-Fink, Sandor Balog, Aaron Lee & Barbara Drasler

  56. Department of Chemistry, University of Fribourg, Fribourg, Switzerland

    Barbara Rothen-Rutishauser

  57. Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK, USA

    Stefan Wilhelm, Handan Acar & Roger G. Harrison

  58. Stephenson Cancer Center, Oklahoma City, OK, USA

    Stefan Wilhelm, Handan Acar, Roger G. Harrison, Chuanbin Mao, Priyabrata Mukherjee & Rajagopal Ramesh

  59. School of Chemical, Biological and Materials Engineering, University of Oklahoma, Norman, OK, USA

    Roger G. Harrison

  60. Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK, USA

    Chuanbin Mao

  61. School of Materials Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, China

    Chuanbin Mao

  62. Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA

    Priyabrata Mukherjee & Rajagopal Ramesh

  63. Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC, USA

    Lacey R. McNally

  64. Department of Bioengineering, Wake Forest School of Medicine, Winston-Salem, NC, USA

    Lacey R. McNally

  65. Department of Transplantation Medicine, Mayo Clinic, Jacksonville, FL, USA

    Sara Busatto & Joy Wolfram

  66. Department of Physiology and Biomedical Engineering, Mayo Clinic, Jacksonville, FL, USA

    Sara Busatto & Joy Wolfram

  67. Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy

    Sara Busatto & Paolo Bergese

  68. CSGI, Research Center for Colloids and Nanoscience, Florence, Italy

    Sara Busatto & Paolo Bergese

  69. Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, USA

    Joy Wolfram & Mauro Ferrari

  70. Department of Medicine, Weill Cornell Medicine, Weill Cornell Medicine, New York, NY, USA

    Mauro Ferrari

  71. Department of NanoEngineering, Chemical Engineering Program, University of California, San Diego, La Jolla, CA, USA

    Ronnie H. Fang

  72. Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA

    Liangfang Zhang

  73. Department of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, TX, USA

    Jie Zheng, Chuanqi Peng, Bujie Du & Mengxiao Yu

  74. Institute of Biomaterials and Biomedical Engineering, University of Toronto Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada

    Danielle M. Charron

  75. Department of Medical Biophysics, University of Toronto Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada

    Gang Zheng

  76. Nature Nanotechnology, London, UK

    Chiara Pastore

Authors
  1. Hon S. Leong
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Correspondence to Chiara Pastore.

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Leong, H.S., Butler, K.S., Brinker, C.J. et al. On the issue of transparency and reproducibility in nanomedicine. Nat. Nanotechnol. 14, 629–635 (2019). https://doi.org/10.1038/s41565-019-0496-9

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