An FDA-approved iron oxide nanoparticle used for the treatment of anaemia can be repurposed for leukaemia therapy.
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Crichton, R. in Iron Metabolism: From Molecular Mechanisms to Clinical Consequences (ed. Crichton, R.) 22–70 (Wiley, 2016).
Torti, S. V., Manz, D. H., Paul, B. T., Blanchette-Farra, N. & Torti, F. M. Annu. Rev. Nutr. 38, 97–125 (2018).
Daniels, T. R. et al. Biochim. Biophys. Acta 1820, 291–317 (2012).
Pinnix, Z. K. et al. Sci. Transl. Med. 2, 43ra56 (2010).
Gu, Z. et al. Cancer Res. 75, 2211–2221 (2015).
Trujillo-Alonso, V. et al. Nat. Nanotechnol. https://doi.org/10.1038/s41565-019-0406-1 (2019).
Balakrishnan, V. S. et al. Eur. J. Clin. Invest. 39, 489–496 (2009).
Vadhan-Raj, S. et al. Am. J. Hematol. 89, 7–12 (2014).
Zanganeh, S. et al. Nat. Nanotechnol. 11, 986–994 (2016).
Schoenfeld, J. D. et al. Cancer Cell 32, 268 (2017).
Kalinowski, D. S. et al. Biochim. Biophys. Acta 1863, 727–748 (2016).
Toth, G. B. et al. Kidney Int. 92, 47–66 (2017).
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Torti, S.V., Torti, F.M. Winning the war with iron. Nat. Nanotechnol. 14, 499–500 (2019). https://doi.org/10.1038/s41565-019-0419-9