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ALL-DNA SUPERSTRUCTURES

DNA enters a new phase

A phase-separated state is observed with single-stranded DNA composed of ‘polymeric’ blocks and exploited to programme the assembly of micrometre-sized all-DNA colloidal particles.

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Fig. 1: A combination of DNA phase-separation and hybridization yields new all-DNA colloids that could not be realized with each process in isolation.

References

  1. Jones, M. R., Seeman, N. C. & Mirkin, C. A. Science 347, 1260901 (2015).

    Article  Google Scholar 

  2. Macfarlane, R. J. et al. Science 334, 204–208 (2011).

    Article  CAS  Google Scholar 

  3. Trinh, T. et al. Nat. Chem. 10, 184–192 (2018).

    Article  CAS  Google Scholar 

  4. Service, R. F. Science https://doi.org/10.1126/science.aah7240 (2016).

  5. Xiong, H., Sfeir, M. Y. & Gang, O. Nano Lett. 10, 4456–4462 (2010).

    Article  CAS  Google Scholar 

  6. Auyeung, E. et al. J. Am. Chem. Soc. 137, 1658–1662 (2015).

    Article  CAS  Google Scholar 

  7. Merindol, R., Loescher, S., Samanta, A. & Walther, A. Nat. Nanotech. https://doi.org/10.1038/s41565-018-0168-1 (2018).

  8. Kim, H.-C., Park, S.-M. & Hinsberg, W. D. Chem. Rev. 110, 146–177 (2010).

    Article  CAS  Google Scholar 

  9. Mohsen, M. G. & Kool, E. T. Acc. Chem. Res. 49, 2540–2550 (2016).

    Article  CAS  Google Scholar 

  10. Meyvis, T. K. L., De Smedt, S. C., Van Oostveldt, P. & Demeester, J. Pharmaceut. Res. 16, 1153–1162 (1999).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Chad A. Mirkin or Sarah Hurst Petrosko.

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Mirkin, C.A., Petrosko, S.H. DNA enters a new phase. Nature Nanotech 13, 624–625 (2018). https://doi.org/10.1038/s41565-018-0229-5

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