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Viral infection

How influenza shuts down host transcription

Influenza A virus can selectively recognize and degrade host transcripts via a specific molecular motif, facilitating modulation of the host immune response.

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Fig. 1: Self or non-self recognition by influenza virus PA-X.

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Correspondence to Christopher B. Brooke.

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Rivera-Cardona, J., Brooke, C.B. How influenza shuts down host transcription. Nat Microbiol 8, 1195–1196 (2023). https://doi.org/10.1038/s41564-023-01416-9

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