Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

ANTIVIRALS

Emerging antiviral resistance

Nature Microbiology volume 5, pages 4–5 (2020)Cite this article

Subjects

Baloxavir marboxil (BXM) represents a promising advance in antiviral chemotherapies for influenza infections. Identification of transmissible BXM-resistant strains in Japan may hit pause on widespread adoption of this therapy and could lead to revision of surveillance practices for emerging viruses.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Transmissibility of antiviral resistance mutations.

References

  1. Lee, N. & Hurt, A. C. Curr. Opin. Infect. Dis. 31, 520–526 (2018).

    Article  CAS  Google Scholar 

  2. Shtyrya, Y. A., Mochalova, L. V. & Bovin, N. V. Acta Naturae 2, 26–32 (2009).

    Article  Google Scholar 

  3. FDA approves new drug to treat influenza. U. S. Food and Drug Administration https://www.fda.gov/news-events/press-announcements/fda-approves-new-drug-treat-influenza (2018).

  4. Imai, M. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-019-0609-0 (2019).

  5. Omoto, S. et al. Sci. Rep. 8, 9633 (2018).

    Article  Google Scholar 

  6. Noshi, T. et al. Antiviral Res. 160, 109–117 (2018).

    Article  CAS  Google Scholar 

  7. Bloom, J. D., Gong, L. I. & Baltimore, D. Science 328, 1272–1275 (2010).

    Article  CAS  Google Scholar 

  8. Moscona, A. New Engl. J. Med. 360, 953–956 (2009).

    Article  CAS  Google Scholar 

  9. Frise, R. et al. Sci. Rep. 6, 29793 (2016).

    Article  CAS  Google Scholar 

  10. Baym, M., Stone, L. K. & Kishony, R. Science 351, aad3292 (2016).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Biology Department, Bethany College, Bethany, WV, USA

    Karen A. Kormuth

  2. Department of Microbiology & Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

    Seema S. Lakdawala

  3. Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

    Seema S. Lakdawala

Authors
  1. Karen A. Kormuth
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Seema S. Lakdawala
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Seema S. Lakdawala.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kormuth, K.A., Lakdawala, S.S. Emerging antiviral resistance. Nat Microbiol 5, 4–5 (2020). https://doi.org/10.1038/s41564-019-0639-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41564-019-0639-7

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing