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PARASITE GENOMICS

Evolution of Cryptosporidium

A large-scale comparative genomic survey of Cryptosporidium species and subtypes reveals a cryptic anthroponotic Cryptosporidium parvum branch and a large, recent superclade of species and subtypes that undergo genetic exchange, potentially facilitating host associations.

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Fig. 1: A Cryptosporidium superclade and recombination events detected thus far.

References

  1. Kotloff, K. L. et al. Lancet 382, 209–222 (2013).

    Article  Google Scholar 

  2. GBD Diarrhoeal Diseases Collaborators. Lancet Infect. Dis. 17, 909–948 (2017).

    Article  Google Scholar 

  3. Morgan-Ryan, U. M. et al. J. Eukaryot. Microbiol. 49, 433–440 (2002).

    Article  Google Scholar 

  4. Zahedi, A. et al. Int. J. Parasitol. 47, 601–607 (2017).

    Article  CAS  Google Scholar 

  5. Nader, J. L. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-019-0377-x (2019).

    Article  CAS  Google Scholar 

  6. Xu, P. et al. Nature 431, 1107–1112 (2004).

    Article  CAS  Google Scholar 

  7. Abrahamsen, M. S. Science 304, 441–445 (2004).

    Article  CAS  Google Scholar 

  8. Feng, Y., Ryan, U. M. & Xiao, L. Trend. Parasitol. 34, 997–1011 (2018).

    Article  CAS  Google Scholar 

  9. Tzipori, S. & Widmer, G. Trend. Parasitol. 24, 184–189 (2008).

    Article  Google Scholar 

  10. Gilchrist, C. A. et al. J. Infect. Dis. 218, 259–264 (2018).

    Article  CAS  Google Scholar 

  11. Vinayak, S. et al. Nature 523, 477–480 (2015).

    Article  CAS  Google Scholar 

  12. Morada, M. et al. Int. J. Parasitol. 46, 21–29 (2016).

    Article  CAS  Google Scholar 

  13. Josse, L., Bones, A. J., Purton, T., Michaelis, M. & Tsaousis, A. D. Curr. Prot. Microbiol. https://doi.org/10.1002/cpmc.80 (2019).

  14. Checkley, W. et al. Lancet Infect. Dis. 15, 85–94 (2015).

    Article  Google Scholar 

Download references

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Correspondence to Jessica C. Kissinger.

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Kissinger, J.C. Evolution of Cryptosporidium. Nat Microbiol 4, 730–731 (2019). https://doi.org/10.1038/s41564-019-0438-1

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