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Synthetic methodology

Chiral sulfinyls from sulfones

Nature Chemistry volume 15, pages 165–166 (2023)Cite this article

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The selective removal of one oxygen atom from sulfones, without over-reduction to sulfide, is a challenging task. Now, through organocatalysis and incorporation of a cyano group into the sulfone, an asymmetric deoxygenation strategy has been developed, providing an efficient method for the synthesis of chiral sulfinyl compounds.

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Fig. 1: Routes to chiral sulfinyl compounds.

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Authors and Affiliations

  1. Faculty of Chemistry, Wrocław University of Science and Technology, Wrocław, Poland

    Elżbieta Wojaczyńska

  2. Faculty of Chemistry, University of Wrocław, Wrocław, Poland

    Jacek Wojaczyński

Authors
  1. Elżbieta Wojaczyńska
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  2. Jacek Wojaczyński
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Correspondence to Elżbieta Wojaczyńska.

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The authors declare no competing interests.

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Wojaczyńska, E., Wojaczyński, J. Chiral sulfinyls from sulfones. Nat. Chem. 15, 165–166 (2023). https://doi.org/10.1038/s41557-022-01122-9

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