Compound 3l

(R)-2,3-difluoro-6-(1-fluoroethyl)benzaldehyde

From: Controlling Pd(iv) reductive elimination pathways enables Pd(ii)-catalysed enantioselective C(sp3)−H fluorination

View in PubChem | MDL Molfile | Chemdraw file

Synthetic procedure: See article for the definitive version of this procedure and for full experimental details.

1l was fluorinated following general procedure B described for compound 3k (52% NMR yield of 3l). Due to volatility, 3l was directly converted into 5l for characterization.

Back to article page