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Reconstituting the dynamic steady states of actin networks in vitro

Nature Cell Biology volume 26, pages 494–497 (2024)Cite this article

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Despite the constant renewal of their components, cellular actin networks maintain their overall appearance, through a subtle balance of filament assembly and disassembly. This balance is key to the remodelling of cellular architecture. We discuss the significance of in vitro reconstitutions in deciphering the complexity of actin regulation.

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Fig. 1: Dynamic steady states of actin networks.

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Acknowledgements

M.T. and L.B. thank the CytoMorpho Lab for critical reading and providing constructive comments. This work was supported by a European Research Council consolidator grant (771599) and proof-of-concept grant (780458) (to M.T.) and by an advanced grant (741773) (AAA) (to L.B.).

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Authors and Affiliations

  1. Université Paris Sciences et Lettres, CEA, ESPCI, Institut Pierre-Gilles de Gennes, CytoMorpho Lab, Paris, France

    Manuel Théry & Laurent Blanchoin

  2. Université Grenoble-Alpes, CEA, CNRS, INRA, Interdisciplinary Research Institute of Grenoble, CytoMorpho Lab, Grenoble, France

    Manuel Théry & Laurent Blanchoin

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  1. Manuel Théry
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  2. Laurent Blanchoin
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Correspondence to Manuel Théry or Laurent Blanchoin.

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Nature Cell Biology thanks Thomas Pollard and the other, anonymous, reviewer(s) for their contribution to the peer review of this work.

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Théry, M., Blanchoin, L. Reconstituting the dynamic steady states of actin networks in vitro. Nat Cell Biol 26, 494–497 (2024). https://doi.org/10.1038/s41556-024-01379-x

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