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tRNA flux and consistency in differentiation

Nature Cell Biology volume 26, pages 37–38 (2024)Cite this article

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tRNA transcriptome composition and regulation are poorly understood. A study reports tRNA transcriptome reprogramming during human cell differentiation, where the abundance of individual tRNA gene transcripts is drastically changed, but each pool of tRNAs containing the same anticodon remains stable.

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Fig. 1: tRNA transcriptome reprogramming during cell differentiation.

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Authors and Affiliations

  1. Committee on Genetics, Genomics and Systems Biology, University of Chicago, Chicago, IL, USA

    Yichen Hou & Tao Pan

  2. Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA

    Tao Pan

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  1. Yichen Hou
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  2. Tao Pan
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Correspondence to Tao Pan.

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The authors declare no competing interests.

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Hou, Y., Pan, T. tRNA flux and consistency in differentiation. Nat Cell Biol 26, 37–38 (2024). https://doi.org/10.1038/s41556-023-01323-5

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