Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Historical News & Views: Chromatin

Defining the chromatin signature of pluripotency

Nature Cell Biology volume 26, pages 24–25 (2024)Cite this article

Subjects

The interplay between DNA and its associated proteins has a crucial role in regulating gene expression and determining cellular identity. Here we revisit an earlier Nature Cell Biology study that established the chromatin signature associated with pluripotency.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Epigenetic regulation of gene expression in cells.

References

  1. Azuara, V. et al. Nat. Cell Biol. 8, 532–538 (2006).

    Article  CAS  PubMed  Google Scholar 

  2. Harikumar, A. & Meshorer, E. EMBO Rep. 16, 1609–1619 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Ryba, T. et al. Genome Res. 20, 761–770 (2010).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Zhao, P. A., Sasaki, T. & Gilbert, D. M. Genome Biol. 21, 1–20 (2020).

    Article  CAS  Google Scholar 

  5. Leitch, H. G., Surani, M. A. & Hajkova, P. Trends Genet. 32, 592–595 (2016).

    Article  CAS  PubMed  Google Scholar 

  6. Chen, H. et al. Genome Res. 32, 825–837 (2022).

    PubMed  PubMed Central  Google Scholar 

  7. Tosolini, M. et al. Sci. Rep. 8, 5776 (2018).

    Article  PubMed  PubMed Central  Google Scholar 

  8. Xu, W. et al. Nature 591, 317–321 (2021).

    Article  CAS  PubMed  Google Scholar 

  9. Takahashi, K. & Yamanaka, S. Cell 126, 663–676 (2006).

    Article  CAS  PubMed  Google Scholar 

  10. Takahashi, S., Kobayashi, S. & Hiratani, I. Cell. Mol. Life Sci. 75, 1191–1203 (2018).

    Article  CAS  PubMed  Google Scholar 

  11. Chang, P.-H., Chao, H.-M., Chern, E. & Hsu, S.-H. Biomaterials 268, 120575 (2021).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Université Lyon 1, INSERM, Stem Cell and Brain Research Institute U1208, INRAE USC 1361, Bron, France

    Nathalie Beaujean

Authors
  1. Nathalie Beaujean
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Nathalie Beaujean.

Ethics declarations

Competing interests

The author has no conflicts of interest to declare.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Beaujean, N. Defining the chromatin signature of pluripotency. Nat Cell Biol 26, 24–25 (2024). https://doi.org/10.1038/s41556-023-01268-9

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41556-023-01268-9

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing