Bone marrow endothelial cells deliver oxygen and nutrients and regulate bone formation and haematopoiesis in the surrounding microenvironment. A new study identifies a subtype of capillary that occurs exclusively in the epiphysis and displays unique characteristics that have a role in balancing osteogenesis and haematopoiesis.
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References
Butler, J. M. et al. Cell Stem Cell 6, 251–264 (2010).
Lis, R. et al. Nature 545, 439–445 (2017).
Rafii, S., Butler, J. M. & Ding, B. Sen Nature 529, 316–325 (2016).
Tikhonova, A. N. et al. Nature 569, 222 (2019).
Baryawno, N. et al. Cell 177, 1915–1932.e16 (2019).
Hooper, A. T. et al. Cell Stem Cell 4, 263–274 (2009).
Iga, T. et al. Nat. Cell Biol. https://doi.org/10.1038/s41556-023-01240-7 (2023).
Baccin, C. et al. Nat. Cell Biol. 22, 38–48 (2019).
Chen, Y. et al. Nat. Commun. 12, 7199 (2021).
Kusumbe, A. P., Ramasamy, S. K. & Adams, R. H. Nature 507, 323–328 (2014).
Ramasamy, S. K. et al. Nat. Commun. 7, 13601 (2016).
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S.R. is co-founder and non-paid consultant to Angiocrine Bioscience. D.R. declares no competing interests.
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Redmond, D., Rafii, S. The epicentre of haematopoiesis and osteogenesis. Nat Cell Biol 25, 1406–1407 (2023). https://doi.org/10.1038/s41556-023-01242-5
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DOI: https://doi.org/10.1038/s41556-023-01242-5
