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DMRT1 drives the human germline forward

Nature Cell Biology volume 25, pages 1408–1410 (2023)Cite this article

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The molecular program of human germline commitment remains largely unknown. A new study delineates the multifaceted functions of DMRT1 in human germline development, particularly in the transition from early to late primordial germ cells.

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Fig. 1: Schematic diagram of the molecular regulatory network of human germline development and the extensive role of DMRT1.

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Author notes

  1. These authors contributed equally: Yongjie Lu, Peng Yuan.

Authors and Affiliations

  1. State Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China

    Yongjie Lu, Peng Yuan & Jie Qiao

Authors
  1. Yongjie Lu
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  2. Peng Yuan
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  3. Jie Qiao
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Corresponding author

Correspondence to Jie Qiao.

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The authors declare no competing interests.

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Cite this article

Lu, Y., Yuan, P. & Qiao, J. DMRT1 drives the human germline forward. Nat Cell Biol 25, 1408–1410 (2023). https://doi.org/10.1038/s41556-023-01196-8

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