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Immunometabolism

Host protection by two memory-like MAIT subsets

Nature Cell Biology volume 25, pages 802–804 (2023)Cite this article

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How mucosal-associated invariant T (MAIT) cells acquire memory-like features after infection and the factors that control this process have been unclear. A study now defines two subsets of antigen-adapted MAIT cells emerging after immunization that differ in functions, lung localization and metabolic requirements.

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Fig. 1: Two populations of antigen-adapted MAIT cells originate after Salmonella infection resolution.

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  1. Department of Infectious Diseases, Faculty of Medicine, Imperial College London, London, UK

    Margarita Dominguez-Villar

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  1. Margarita Dominguez-Villar
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Correspondence to Margarita Dominguez-Villar.

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The author has no competing interests.

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Dominguez-Villar, M. Host protection by two memory-like MAIT subsets. Nat Cell Biol 25, 802–804 (2023). https://doi.org/10.1038/s41556-023-01149-1

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