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Dissecting melanocytes to predict melanoma

With advanced high-throughput technologies, scientists can now use transcriptional signatures to study melanocytes as they become cancer. A new study identifies transcriptional programs at single-cell resolution across platforms and species, which enables prediction of melanoma prognosis and response to immune-checkpoint inhibitor therapy.

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Fig. 1: Melanoma subtypes categorised by transcriptional signature.


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Correspondence to Leonard I. Zon.

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McConnell, A.M., Zon, L.I. Dissecting melanocytes to predict melanoma. Nat Cell Biol 23, 930–931 (2021).

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