A transitional stem cell state in the lung

Studies of stem cell behaviour during regeneration have largely focused on understanding how cells make the choice between self-renewal and differentiation. It remains unclear whether cells undergo smooth transitions during differentiation or pause at selective intermediate states. Three studies now explore this question in lung regeneration.

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Fig. 1: Response of the lung alveolar epithelial cells to injury.


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Correspondence to Xin Sun.

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Verheyden, J.M., Sun, X. A transitional stem cell state in the lung. Nat Cell Biol 22, 1025–1026 (2020).

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