Tendons have limited regenerative potential, and injuries often cause scarring. A study now identifies a tendon stem cell population that contributes to regeneration and a tendon fibro–adipogenic progenitor population involved in fibrosis.
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References
Titan, A. L., Foster, D. S., Chang, J. & Longaker, M. T. Plast. Reconstr. Surg. 144, 639e–647e (2019).
Juneja, S. C. & Veillette, C. A. Arthritis 2013, 154812 (2013).
Kannus, P. Scand. J. Med. Sci. Sports 10, 312–320 (2000).
Killian, M. L., Cavinatto, L., Galatz, L. M. & Thomopoulos, S. J. Shoulder Elbow Surg. 21, 228–237 (2012).
Snedeker, J. G. & Foolen, J. Acta Biomater. 63, 18–36 (2017).
Zhang, J. & Wang, J. H. Methods Mol. Biol. 1842, 217–228 (2018).
Bi, Y. et al. Nat. Med. 13, 1219–1227 (2007).
Harvey, T., Flamenco, S. & Fan, C.- M. Nat. Cell Biol. https://doi.org/10.1038/s41556-019-0417-z (2019).
Staverosky, J. A., Pryce, B. A., Watson, S. S. & Schweitzer, R. Dev. Dyn. 238, 685–692 (2009).
Chan, C. K. et al. Cell 160, 285–298 (2015).
Chan, C. K. F. et al. Cell 175, 43–56.e21 (2018).
Evrova, O. & Buschmann, J. Eur. Cell. Mater. 34, 15–39 (2017).
Hu, M. S., Moore, A. L. & Longaker, M. T. J. Invest. Dermatol. 138, 729–730 (2018).
Rinkevich, Y. et al. Science 348, aaa2151 (2015).
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Titan, A.L., Longaker, M.T. A fine balance in tendon healing. Nat Cell Biol 21, 1466–1467 (2019). https://doi.org/10.1038/s41556-019-0432-0
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DOI: https://doi.org/10.1038/s41556-019-0432-0