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Mitochondrial OXPHOS complex assembly lines

Nature Cell Biologyvolume 20pages511513 (2018) | Download Citation

Mitochondria are critical for cellular energy generation and house oxidative phosphorylation (OXPHOS) complexes, which are under dual genetic control. A study finds that transcript translation and complex assembly are partitioned, and OXPHOS complexes III, IV and V are built at spatially defined regions of the mitochondrial inner membrane.

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Author information

Affiliations

  1. Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia

    • Luke E. Formosa
    •  & Michael T. Ryan

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Competing interests

The authors declare no competing interests.

Corresponding author

Correspondence to Michael T. Ryan.

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DOI

https://doi.org/10.1038/s41556-018-0098-z

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