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CANCER

Size matters in nanoscale communication

Exosomes are heterogeneous, nanoscale vesicles that mediate cellular communication. A study now leverages a size separation strategy to identify sub-classes of nanoparticles, revealing a subtype without an encapsulating membrane and variation in vesicle cargo, suggesting that size is not the only driver of heterogeneity.

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Fig. 1: Schematic representation of vesicle subpopulations that comprise the cellular communication milieu.

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Correspondence to Dolores Di Vizio.

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Zijlstra, A., Di Vizio, D. Size matters in nanoscale communication. Nat Cell Biol 20, 228–230 (2018). https://doi.org/10.1038/s41556-018-0049-8

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