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Screening for drivers of SARS-CoV-2 uptake

Nature Biomedical Engineering volume 8, pages 205–206 (2024)Cite this article

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Genetic and cellular drivers of the cellular uptake of SARS-CoV-2 can be screened at high throughput via droplet microfluidics and size-exclusion methods for the analysis of the formation of fusions between cells expressing the virus’s spike protein and cells expressing the protein’s receptor.

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Fig. 1: High-throughput screening of drivers of syncytium formation between cells expressing the spike protein of SARS-CoV-2 and cells expressing the ACE2 receptor.

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Authors and Affiliations

  1. Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

    Alexis Autour & Christoph A. Merten

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  1. Alexis Autour
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  2. Christoph A. Merten
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Correspondence to Christoph A. Merten.

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The authors declare no competing interests.

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Autour, A., Merten, C.A. Screening for drivers of SARS-CoV-2 uptake. Nat. Biomed. Eng 8, 205–206 (2024). https://doi.org/10.1038/s41551-023-01170-7

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