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Deep screening of antibody–antigen affinities

Nature Biomedical Engineering volume 8, pages 203–204 (2024)Cite this article

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The discovery of antibodies that bind with high affinity to clinically relevant antigens can be sped up by leveraging next-generation sequencing to screen hundreds of millions of antibody–antigen interactions.

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Fig. 1: Workflow of deep screening of antibody–antigen interactions.

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  1. Department of Chemical and Biological Engineering, University of Colorado, Boulder, CO, USA

    Timothy A. Whitehead

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  1. Timothy A. Whitehead
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Correspondence to Timothy A. Whitehead.

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Whitehead, T.A. Deep screening of antibody–antigen affinities. Nat. Biomed. Eng 8, 203–204 (2024). https://doi.org/10.1038/s41551-023-01169-0

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