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Lab-on-a-chip devices

Rapid deformability cytometry for tissue biopsies

The physical phenotypes of malignant cells in tissue biopsies can be rapidly characterized at high throughput via deformability cytometry after singularizing the cells into a suspension by using a tissue grinder.

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Fig. 1: Workflow for real-time fluorescence deformability cytometry, from tissue dissociation to sample classification.

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Correspondence to Dino Di Carlo.

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Competing interests

D.D.C. and the Regents of the University of California have financial interests in Cytovale Inc., which is commercializing deformability cytometry technology.

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Di Carlo, D. Rapid deformability cytometry for tissue biopsies. Nat. Biomed. Eng 7, 1337–1339 (2023). https://doi.org/10.1038/s41551-023-01110-5

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