Confining the Zika virus within a self-adjuvanting hydrogel that forms a subcutaneous inflammatory niche stimulates strong immune responses in mice without inducing infection.
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The authors declare no competing interests.
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Gong, N., Hamilton, A.G. & Mitchell, M.J. A hydrogel-entrapped live virus immunization. Nat. Biomed. Eng (2023). https://doi.org/10.1038/s41551-023-01008-2