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Using extracellular vesicles in blood to diagnose paediatric tuberculosis

Multiplex detection of two interacting Mycobacterium tuberculosis biomarkers on the surface of circulating extracellular vesicles, using a nanoplasmon-enhanced immunoassay, improves the diagnosis of tuberculosis in immunosuppressed children living with HIV.

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Fig. 1: Schematic of a NEI for diagnosing TB.


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This is a summary of: Zheng, W. et al. Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples. Nat. Biomed. Eng. (2022).

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Using extracellular vesicles in blood to diagnose paediatric tuberculosis. Nat. Biomed. Eng 6, 930–931 (2022).

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