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MECHANOPATHOLOGY

Less fibrosis around softer silicone implants

Nature Biomedical Engineering volume 5, pages 1407–1408 (2021)Cite this article

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Softening the surface of silicone implants reduces their fibrotic encapsulation.

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Fig. 1: Mitigation of the fibrotic encapsulation of silicone implants via soft coatings or through the inhibition of the binding of specific integrins.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Translational Tissue Engineering Center, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA

    Stuart J. Bauer & Joshua C. Doloff

  2. Department of Materials Science and Engineering, Institute of NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA

    Joshua C. Doloff

Authors
  1. Stuart J. Bauer
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  2. Joshua C. Doloff
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Correspondence to Joshua C. Doloff.

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The authors declare no competing interests.

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Bauer, S.J., Doloff, J.C. Less fibrosis around softer silicone implants. Nat Biomed Eng 5, 1407–1408 (2021). https://doi.org/10.1038/s41551-021-00830-w

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