In tendon cells under shear stress, the induction of an influx of calcium by the mechanosensitive ion channel PIEZO1 upregulates collagen crosslinking, which increases tendon stiffness and potentially improves jumping performance.
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Eekhoff, J.D., Iannucci, L.E. & Lake, S.P. Shear mechanosensing drives tendon adaptation. Nat Biomed Eng 5, 1409–1410 (2021). https://doi.org/10.1038/s41551-021-00724-x
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DOI: https://doi.org/10.1038/s41551-021-00724-x