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REGENERATIVE MECHANOBIOLOGY

Stretch-boosted cell-mediated vascularization

Nature Biomedical Engineering volume 5, pages 6–7 (2021)Cite this article

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The capacity of mesenchymal stromal cells to promote vascular regeneration in vivo can be enhanced by the combination of specific small-molecule inhibitors and the right waveform of mechanical stretch.

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Fig. 1: Mechanopharmacological regulation of the vascularization capacity of MSCs.

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Authors and Affiliations

  1. Translational Biology & Engineering Program, Ted Rogers Centre for Heart Research, Toronto, Ontario, Canada

    Craig A. Simmons & Ronald G. Ireland

  2. Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

    Craig A. Simmons & Ronald G. Ireland

  3. Department of Mechanical & Industrial Engineering, University of Toronto, Toronto, Ontario, Canada

    Craig A. Simmons

Authors
  1. Craig A. Simmons
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  2. Ronald G. Ireland
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Correspondence to Craig A. Simmons.

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Simmons, C.A., Ireland, R.G. Stretch-boosted cell-mediated vascularization. Nat Biomed Eng 5, 6–7 (2021). https://doi.org/10.1038/s41551-020-00680-y

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