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DISEASE MODELLING

Load-induced osteoarthritis on a chip

Nature Biomedical Engineering volume 3, pages 502–503 (2019)Cite this article

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An osteoarthritis model in a cartilage-on-a-chip, enabled by hyperphysiological compression, recapitulates the progression of the disease and its response to drugs.

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Fig. 1: Induction of an OA phenotype in a cartilage-on-a-chip.

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Authors and Affiliations

  1. Biomaterials and Bioengineering Laboratory, Division of Pulmonology, Department of Pediatrics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Riccardo Gottardi

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  1. Riccardo Gottardi
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Correspondence to Riccardo Gottardi.

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Gottardi, R. Load-induced osteoarthritis on a chip. Nat Biomed Eng 3, 502–503 (2019). https://doi.org/10.1038/s41551-019-0427-y

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