High-speed optoacoustic tomography can monitor the neural activity of a whole mouse brain, by using a genetically encoded calcium sensor originally developed for fluorescence microscopy.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Vincent, P. et al. EMBO Rep. 11, 1154–1161 (2006).
Yao, J. & Wang, L. V. Curr. Opin. Chem. Biol. 45, 104–112
Gottschalk, S. et al. Nat. Biomed. Eng. https://doi.org/10.1038/s41551-019-0372-9 (2019).
Wang, L. V. & Yao, J. Nat. Methods 13, 627–638 (2016).
Deán-Ben, X. L. et al. Light Sci. Appl. 5, e16201 (2016).
Marvin, J. S. et al. Nat. Methods 10, 162–170 (2013).
Patriarchi, T. et al. Science 360, eaat4422 (2018).
Miao, Q. & Pu, K. Bioconjug. Chem. 27, 2808–2823 (2016).
Knox, H. J. & Chan, J. Acc. Chem. Res. 51, 2897–2905 (2018).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Andreoni, A., Tian, L. Maps of neuronal activity across the mouse brain. Nat Biomed Eng 3, 335–336 (2019). https://doi.org/10.1038/s41551-019-0403-6
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41551-019-0403-6