CANCER NANOMEDICINE

Efficient siRNA delivery with non-cationic carriers

Self-assembled weakly negative nanoparticles bearing an octet of short interfering RNAs, targeting ligands and endosomolytic peptides lead to efficient gene silencing in a mouse model of prostate cancer.

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Fig. 1: Non-cationic nanostructures for in vivo gene silencing via RNAi.

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Correspondence to Chung Hang Jonathan Choi.

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