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GENOME EDITING

Enhanced precision and efficiency

Nature Biomedical Engineering volume 1, pages 856–857 (2017)Cite this article

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The expression of two DNA repair factors improves the recombination of single-stranded oligodeoxynucleotides with Cas9-induced double-strand breaks, facilitating precise and efficient gene editing.

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Fig. 1: Schematic of the DSB-repair pathways used in Cas9-induced genome editing.

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Authors and Affiliations

  1. The Max-Delbrück-Center for Molecular Medicine, Berlin, Germany

    Sanum Bashir & Ralf Kühn

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  1. Sanum Bashir
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  2. Ralf Kühn
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Correspondence to Ralf Kühn.

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Bashir, S., Kühn, R. Enhanced precision and efficiency. Nat Biomed Eng 1, 856–857 (2017). https://doi.org/10.1038/s41551-017-0159-9

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