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GENOME EDITING

Nanoparticles for CRISPR–Cas9 delivery

The DNA mutation that causes Duchenne muscular dystrophy in mice can be corrected, with minimal off-target effects, by gold nanoparticles carrying the CRISPR components.

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Fig. 1: Genome editing via nanoparticle-mediated delivery of the CRISPR–Cas9 machinery.

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Correspondence to Qiaobing Xu.

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Glass, Z., Li, Y. & Xu, Q. Nanoparticles for CRISPR–Cas9 delivery. Nat Biomed Eng 1, 854–855 (2017). https://doi.org/10.1038/s41551-017-0158-x

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  • DOI: https://doi.org/10.1038/s41551-017-0158-x

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