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Genetic engineering: Lassoing genomic libraries

Long single-stranded DNA probes enable the capture and multiplexed cloning of DNA at the megabase scale.

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Figure 1: DNA libraries used in multiplexed assays.
Figure 2: Target capture via a LASSO probe.


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Correspondence to Sriram Kosuri.

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Lubock, N., Kosuri, S. Genetic engineering: Lassoing genomic libraries. Nat Biomed Eng 1, 0098 (2017).

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