A system consisting of an aptamer-based microfluidic biosensor and a simple feedback-control algorithm adjusts therapeutic dosing in near real time in small animals.
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Karnik, R. Drug delivery: Closed-loop dynamic dosing. Nat Biomed Eng 1, 0072 (2017). https://doi.org/10.1038/s41551-017-0072
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DOI: https://doi.org/10.1038/s41551-017-0072
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