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Clinical prospects of liquid biopsies

Nature Biomedical Engineering volume 1, Article number: 0065 (2017) Cite this article

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The clinical utility of diagnostic markers extracted from liquid biopsies from cancer patients is hampered by knowledge gaps in biological understanding but can be aided by technological developments.

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Figure 1: Circulating tumour cells (CTCs), circulating tumour-derived DNA (ctDNA) and exosomes as complementary blood-based biomarkers.

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Authors and Affiliations

  1. Department of Cell and Tissue Biopathology of Tumors, Catherine Alix-Panabières is at the Laboratory of Rare Human Circulating Cells, University Medical Centre, and at the EA2415–Help for Personalized Decision: Methodological Aspects, University Institute of Clinical Research, Montpellier University, 641 avenue du Doyen Gaston Giraud, 34093 Montpellier Cedex 5, France.,

    Catherine Alix-Panabières

  2. Klaus Pantel is in the Department of Tumor Biology, Center of Experimental Medicine, University Medical Centre Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.,

    Klaus Pantel

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  1. Catherine Alix-Panabières
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  2. Klaus Pantel
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Correspondence to Catherine Alix-Panabières or Klaus Pantel.

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Alix-Panabières, C., Pantel, K. Clinical prospects of liquid biopsies. Nat Biomed Eng 1, 0065 (2017). https://doi.org/10.1038/s41551-017-0065

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