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Gene delivery: Suddenly squeezed and shocked

Nature Biomedical Engineering volume 1, Article number: 0047 (2017) | Download Citation

A microfluidic device that integrates mechanical squeezing and electrical stimulation delivers DNA to the nucleus of cells at a rate of millions of cells per minute.

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Affiliations

  1. Mehmet Toner is at the Center for Engineering in Medicine and BioMicroElectroMechanical Systems Resource Center, Massachusetts General Hospital and Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, USA.

    • Mehmet Toner

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Correspondence to Mehmet Toner.

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DOI

https://doi.org/10.1038/s41551-017-0047