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Immune monitoring and treatment in immune-mediated inflammatory diseases

Nature Communications volume 13, Article number: 3245 (2022) Cite this article

Immune-mediated inflammatory diseases (IMIDs) can occur in a number of organ systems as a result of aberrant innate and adaptive immune responses to genetic and environmental triggers. Immune-monitoring technologies are used to detect disease-relevant immune biomarkers, either to enable diagnosis or monitor response to therapy. Immune monitoring is predominantly used in the research setting at present but routine clinical use is increasing. This poster explores the mechanisms underlying a number of common IMIDs, biomarkers relevant to the diagnosis or monitoring of IMIDs, and therapies used to treat these diseases.

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Authors and Affiliations

  1. Center for Translational Immunology, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands

    Femke van Wijk, Marjolein de Bruin, Helen Leavis & Stefan Nierkens

  2. National Expertise Center for Atopic Dermatitis, Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, The Netherlands

    Marjolein de Bruin

  3. Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands

    Helen Leavis

  4. Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands

    Stefan Nierkens

Authors
  1. Femke van Wijk
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  2. Marjolein de Bruin
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  3. Helen Leavis
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  4. Stefan Nierkens
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Corresponding author

Correspondence to Femke van Wijk.

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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van Wijk, F., de Bruin, M., Leavis, H. et al. Immune monitoring and treatment in immune-mediated inflammatory diseases. Nat Commun 13, 3245 (2022). https://doi.org/10.1038/s41467-022-30891-7

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  • DOI: https://doi.org/10.1038/s41467-022-30891-7

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