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Relationship between blood pressure repeatedly measured by a wrist-cuff oscillometric wearable blood pressure monitoring device and left ventricular mass index in working hypertensive patients

Hypertension Research volume 45, pages 87–96 (2022)Cite this article

Abstract

This study sought to evaluate the relationship between blood pressure (BP) taken by a new wrist-cuff oscillometric wearable BP monitoring device and left ventricular mass index measured by cardiac magnetic resonance imaging (cMRI-LVMI) in 50 hypertensive patients (mean age 60.5 ± 8.9 years, 92.0% men, 96% treated for hypertension) with regular employment. Participants were asked to self-measure their wearable BPs twice in the morning and evening under a guideline-recommended standardized home BP measurement, and once each at five predetermined times and any additional time points under an ambulatory condition for a maximum of 7 days. In total, 2105 wearable BP measurements (home BP: 747 [morning: 409, evening: 338], ambulatory condition: 1358 [worksite: 942]) were collected over 5.5 ± 1.2 days. The average of all wearable systolic BP (SBP) readings (129.8 ± 11.0 mmHg) was weakly correlated with cMRI-LVMI (r = 0.265, p = 0.063). Morning home wearable SBP average (128.5 ± 13.8 mmHg) was significantly correlated with cMRI-LVMI (r = 0.378, p = 0.013), but ambulatory wearable SBP average (132.5 ± 12.7 mmHg) was not (r = 0.215, p = 0.135). The averages of the highest three values of all wearable SBPs (153.3 ± 13.9 mmHg) and ambulatory wearable SBPs (152.9 ± 13.9 mmHg) were 16 mmHg higher than that of the morning home wearable SBPs (137.0 ± 15.9 mmHg). Those peak values were significantly correlated with cMRI-LVMI (r = 0.320, p = 0.023; r = 0.310, p = 0.029; r = 0.451, p = 0.002, respectively). In conclusion, an increased number of wearable BP measurements, which could detect individual peak BP, might add to the clinical value of these measurements as a complement to the guideline-recommended home BP measurements, but further studies are needed to confirm these findings.

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Acknowledgements

The HeartGuide device was supplied by Omron Healthcare Co., Ltd., who also provided funding for the study. However, the collection and analysis of BP data in this study were entirely independent of Omron Healthcare Co., Ltd.

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Authors and Affiliations

  1. Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan

    Kazuomi Kario, Naoko Tomitani, Tomoko Morimoto & Hiroshi Kanegae

  2. Genki Plaza Medical Center for Health Care, Tokyo, Japan

    Hiroshi Kanegae

  3. UCL Institute of Cardiovascular Sciences, University College London, London, UK

    Peter Lacy & Bryan Williams

Authors
  1. Kazuomi Kario
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  2. Naoko Tomitani
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  4. Hiroshi Kanegae
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  6. Bryan Williams
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Contributions

K.K. supervised the conduct of the study and data analysis, and had primary responsibility of writing this paper. N.T. analyzed the data and wrote the paper with input from all authors. T.M. supported study data collection at Washiya Hospital. H.K. contributed to the analysis. P.L. and B.W. contributed to the study design. All authors discussed the results and contributed to the final manuscript.

Funding

This study was financially supported by Omron Healthcare.

Corresponding author

Correspondence to Kazuomi Kario.

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Conflict of interest

KK has received a research grant from Omron Healthcare, A&D and Fukuda Denshi. NT was the recipient of a JSPS KAKENHI grant (no. 20K17127). BW has received a research grant from Omron Healthcare.

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Kario, K., Tomitani, N., Morimoto, T. et al. Relationship between blood pressure repeatedly measured by a wrist-cuff oscillometric wearable blood pressure monitoring device and left ventricular mass index in working hypertensive patients. Hypertens Res 45, 87–96 (2022). https://doi.org/10.1038/s41440-021-00758-3

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