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References
Vu, L. P., Cheng, Y. & Kharas, M. G. The biology of m6A RNA methylation in normal and malignant hematopoiesis. Cancer Disco. 9, 25–33 (2019).
Zhang, C., Fu, J. & Zhou, Y. A review in research progress concerning m6A methylation and immunoregulation. Front. Immunol. 10, 922 (2019).
Wang, X. et al. A DNA-methylated sight on autoimmune inflammation network across RA, pSS, and SLE. J. Immunol. Res. 2018, 4390789 (2018).
Tong, J. et al. m6A mRNA methylation sustains Treg suppressive functions. Cell Res. 28, 253–256 (2018).
Wang, H. et al. Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation. Nat. Commun. 10, 1898 (2019).
Han, D. et al. Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1in dendritic cells. Nature 566, 270–274 (2019).
Zong, X. et al. Mettl3 deficiency sustains long-chain fatty acid absorption through suppressing Traf6-dependent inflammation response. J. Immunol. 202, 567–578 (2019).
Zhang, Y. et al. RNA-binding protein YTHDF3 suppresses interferon-dependent antiviral responses by promoting FOXO3 translation. Proc. Natl. Acad. Sci. USA. 116, 976–981 (2019).
Rubio, R. M., Depledge, D. P., Bianco, C., Thompson, L. & Mohr, I. RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β. Genes Dev. 32, 1472–1484 (2018).
Chen, Y. G. et al. N6-methyladenosine modification controls circular RNA immunity. Mol. Cell S1097–2765, 30546–30555 (2019).
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Paramasivam, A., Priyadharsini, J.V. & Raghunandhakumar, S. Implications of m6A modification in autoimmune disorders. Cell Mol Immunol 17, 550–551 (2020). https://doi.org/10.1038/s41423-019-0307-0
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DOI: https://doi.org/10.1038/s41423-019-0307-0
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